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Long-term Consequences of HCV Infection

                       

What are the chances of persons with HCV infection developing long term infection, chronic liver disease, cirrhosis, liver cancer, or dying as a result of hepatitis C?

Of every 100 persons infected with HCV about:

  • 85 persons may develop long-term infection,

  • 70 persons may develop chronic liver disease,

  • 15 persons may develop cirrhosis over a period of 20 to 30 years, and

  • 5 persons may die from the consequences of long term infection (liver cancer or cirrhosis).

Do medical conditions outside the liver occur in persons with chronic hepatitis C?
A small percentage of persons with chronic hepatitis C develop medical conditions outside the liver (this is called extrahepatic).

These conditions are thought to occur due to the body's natural immune system fighting against itself. Such conditions include:  glomerulonephritis, essential mixed cryoglobulinemia, and porphyria cutanea tarda

 

Attention 2008 Article: Extra-hepatic manifestation of hepatitis C virus infection

Page One

Abdominal Pain and Liver Disease (Liver Pain)

Aplastic Anemia

Anemia and HCV

Arthritis  

Arthritis: Extrahepatic Manifestations: Rheumatological Conditions

Ask the Expert: The Relation Between Arthritis, Hepatitis C and Fibromyalgia

Ascites, the accumulation of fluid in the abdomen, can be a life-threatening condition

Autoimmune Hepatitis

No one is immune from autoimmune hepatitis

Also see our Autoimmune Hepatitis Pages

The Connection Between Hepatitis C
and Autoimmune Disorders

Autonomic Overactivity

Bones and Joints (also Neuropathy)

Bone Loss and HCV

Chronic Hepatitis C May Contribute to an Elevated Risk of Bone Fractures in Postmenopausal Women

Continue reading "Hepatitis C Complication: Breast Cancer"


Page Two

Cardiomyopathy

Chronic fatigue

Cirrhosis

Cirrhosis: Improving Quality Of Life For Patients With Cirrhosis

Reversibility of hepatic fibrosis and cirrhosis-is it all hype? Editorial

Body composition, muscle function, and energy expenditure in patients with liver cirrhosis: a comprehensive study

Cognitive Dysfuntion (FOG)

 Improved cognitive function as a consequence of hepatitis C virus treatment  

Also:HCV & Neurologic Dysfunction)Crohns Disease (Irritable  Bowel)

Cryoglobulinemia

Hepatitis C Associated Systemic Cryoglobulinemia: Successful Treatment With Plasma Exchange

Essential Cryoglobulinemic Vasculitis

Extrahepatic Manifestations: Essential Cryoglobulinemic Vasculitis


Page Three

Dental (caring for our teeth and HCV)

Depression

Diabetes

Diabetes Tied To Recurrence of HCV-Related Liver Cancer

Diabetes Therapy Improves Peg/RBV Response

Diabetes and Liver Disease

Diabetes:Insulin Resistance Inflames The Liver in HCV -

Hepatitis C strongly linked to type 2 diabetes

Diabetes, HCV and Liver Transplanation

Esophageal varices are a life-threatening complication of liver disease

Erythema Nodosum


Page Four

Fatigue and Liver Disease

Fatigue

Sick and Tired

Fatty Liver  (Steatosis)

Fibromyalgia

Extrahepatic Manifestations: Fibromyalgia and Hepatitis C

FDA Approves First Drug for Treating Fibromyalgia

Gallbladder

How You Can Stop HCV from Leading to Gallstones

Glomerulonephritis (Kidney  Disease) 


Page Five

New Data Suggest that Patients with Chronic Liver Disease are at Increased Risk for Heart Disease

Liver and heart: A new link? - ALT Predicts Heart Disease

Hepatitis C and Sleep

Hypersplenism (Spleen)

Spleen Removal Can Help Hepatitis C Patients with Cirrhosis Tolerate Treatment

Spleen?
Do we need it?

Immunopathic or (autoimmune Liver Disease)

HealthWise: Iron Overload

Liver Iron Levels NOT Directly Linked to Fibrosis


Page Six

Lichen Planus

Liver Cancer

New Treatment for Liver Cancer 'Burns Tumors Off' N&N makes cancer breakthrough

Coffee Consumption and Risk of Liver Cancer: A Meta-Analysis. Coffee, 2 Cups Daily, May Reduce Risk for Liver Disease, ALT Elevations -

Lung Problems

Lymphoma & Non-Hodgkin's Lymphoma

Lymphoma Risk Increased with HCV


Page Seven

 Peripheral Neuropathy (PN)

Peripheral Neuropathy: A Study on Prevalence & Characteristics

Porphyria Cutanea Tarda

Extrahepatic Manifestations: Prurigo Nodularis

Pruritus in its most severe form can be debilitating

Raynaud's Disease

Extrahepatic Manifestations:  Raynaud’s Phenomenon


Page Eight

Continue reading "How to Relieve HCV Symptoms"

Steatosis and Liver Cancer

Scleroderma

Sjogren's Syndrome

Skin and HCV (also see Pruritus)

Stroke

Six former Stokes patients have hepatitis C

Hypersplenism (Spleen)

Spleen Removal Can Help Hepatitis C Patients with Cirrhosis Tolerate Treatment

Spleen?
Do we need it?

Systemic Lupus Erythematosus

 


Page Nine

Investigative Eltombopag Shows Promise for Thrombocytopenia in Hepatitis C Patients:

Danazol Increases Platelet Counts in Thrombocytopenia Patients with Chronic Hepatitis C or Cirrhosis

Thyroid Disease

Varices

Vasculitis

Essential Cryoglobulinemic Vasculitis

Waldenstrom Macroglobulinemia

Wilson Disease

Wilson’s Disease: a Genetic but Treatable Liver Disorder

 

       

 

   Interesting Articles on HCV

From AASLD Nov 2007

First Studies Demonstrating Greater than 60% Sustained Viral Response Rates with Half the Standard Treatment Duration in Genotype 1 Chronic Hepatitis C Patients (Vertex press release)


Articles on HCV


Hepatitis C treatment reduces the virus but serious liver problems may progress

Here's how hepatitis C virus evades the body's cell defences

Milk Thistle (Silymarin) Demonstrates Anti-inflammatory and Anti-HCV Activity in a Laboratory Study  

The Pros and Cons of Using Marijuana with Hepatitis C

The Emotional Impact of Leaving Work on Disability

CANNABIS USE AS AN INDEPENDENT PREDICTOR OF SEVERE STEATOSIS DURING CHRONIC HEPATITIS C

Chronic Alcohol Consumption Impairs Immune Response to HCV

The Immune System & Hepatitis C Virus

HealthWise: Men’s Health and HCV

Women and HCV

Reasons Why Patients Infected with Chronic Hepatitis C Virus Choose to Defer Treatment: Do
They Alter Their Decision with Time?
 

HCV affects more then just our Liver

FAQ on Autoimmunity

 Does HCV Replicate Outside The Liver and It's Significance?

   

Extrahepatic Manifestations of HCV:


From HCV ADVOCATE


  PDF Extrahepatic Manifestations (overview)


  PDF Cryoglobulinemia
  PDF Essential Cryoglobulinemic Vasculitis
  PDF Fibromyalgia

  PDF Lichen Planus
  PDF Non-Hodgkin's Lymphoma (NHL)
  PDF Peripheral Neuropathy (PN)
  PDF Porphyria Cutanea Tarda (PCT)
  PDF Pruritus (Itching)
  PDF Raynaud's Phenomenon
  PDF Sjögren’s (Show grins) Syndrome
  PDF Systemic Lupus Erythematosus
  PDF Waldenstrom Macroglobulinemia


From Hep C Challenge

The Immune System & Hepatitis C Virus


From Hiv&Hepatitis Site

Heavy Alcohol Use Worsens Disease Progression in Women with Chronic Hepatitis C  

 

 

 

 

 

 

 
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Reviewed Updated Aug 11 2008