Articles on all genotypes & Latest Treatments

2004

INDEX

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2006 Research

2005 Index of all Genotype Research


Page One : 

2004 Articles

Genotype is the strongest predictor of response to treatment.

24 weeks of peginterferon alfa-2a plus ribavirin as effective as 48 weeks with higher-dose ribavirin for HCV genotype 2 and 3

Nov 03 2004

Peginterferon Alfa- 2b (Peg-Intron) and Ribavirin Combination Therapy in Chronic HCV Genotype 4

Nov 08 2004

SHORT (14 WEEKS) TREATMENT WITH PEGYLATED INTERFERON ALPHA-2B AND RIBAVIRIN IN PATIENTS WITH HEPATITIS C GENOTYPE 2/3 VIRUS INFECTION AND EARLY VIROLOGICAL RESPONSE

Nov 01 2004

HCV Genotype 2 and 3 Have Similar SVR to Peginterferon alfa-2a plus Ribavirin, Regardless of Length of Treatment, Ribavirin Dose, or Baseline Viral Load

Nov 01 2004


Page Two:

Retreatment of Interferon Nonresponders with a Reinforced Regimen Should Be Focused on Genotype 2/3 Patients and Younger Genotype 1/4 Patients

Oct 25 2004

Effects of Ribavirin Combined with Interferon Alfa on Viral Kinetics in Patients with HCV Genotype 1 and High Baseline Viral Load

Oct 25 2004

Different mechanisms of steatosis in hepatitis C virus genotypes 1 and 3 infections

Sep 23 2004

RBV Kinetics--Improves Early Response

Effects of ribavirin combined with interferon-alpha2b on viral kinetics during first 12 weeks of treatment in patients with hepatitis C virus genotype 1 and high baseline viral loads"

Sep 23 2004

Sep 2004

Can You Have Multiple Genotypes?

Sep 03 2004

HCV Therapy Should Depend on Genotype, Doc Says

Aug 11 2004

NEW YORK (Reuters Health) Jul 02 - Infection with hepatitis C virus (HCV) genotype 3 often clears spontaneously, sparing the patient unnecessary treatment, German researchers report in the July issue of the Journal of Medical Virology.

July 02 2004

Peginterferon alfa-2b and Ribavirin for 24 Weeks Sufficient for Genotype 2 or 3 Chronic HCV

June 30 2004

Evidence for a Relation Between the HCV Viral Load and Genotype and HCV-specific T Cell Responses

June 16 04

Peginterferon Alfa-2b (Peg-Intron) plus Ribavirin Treatment in Previously Untreated Patients Infected with HCV Genotype 2 or 3

June 02 04

 


Page Three : 

2004 Articles


Infection with Hepatitis C Virus Genotype 4 in the United States

Cross-Genotype Immunity to Hepatitis C Virus.

HCV Genotype 4

Treatment for Chronic Hepatitis C: Updated Swedish Consensus Guidelines

HCV Patients with Genotype 1b May Show a Sustained Response and ALT Improvement After Prolonged Re-treatment with Interferon Alfa

Efficacy of Early Retreatment with Interferon Beta for Relapse in Patients with Chronic Hepatitis C Genotype Ib

Is a 48-week Course of Treatment with Peginterferon Plus Ribavirin Too Short to Maximize a Sustained Viral Response Among Patients with Hepatitis C virus Genotype 1?

Pegasys plus Copegus: Newly Published Data Reports Highest Overall Sustained Virological Response Ever - 63%- All Genotypes Listed


Page Four

2004 Articles


Peginterferon Alfa-2b (PEG-Intron) Plus Ribavirin Can Cure HCV Genotypes 2 and 3

04-16-04

Schering-Plough Reports New Data Showing Patients with Hepatitis C Genotypes 2 and 3 May Benefit from Shorter Course of Treatment with PegIntron and Rebetol Combination Therapy

Black Patients with HCV Genotype 1 in a Study of Veterans Have a Lower Sustained Viral Response Rate Due to Lower Neutrophil Count

 4-26-04

HCV Genotypes and Pediatric HCV Infection

4-26-04

Twice a Week Administration of PEG-Intron Plus Ribavirin in Obtaining SVR Among Patients with HCV Genotype 1

May 25 04

  

Results of a new study
published in the current issue of the New England Journal of Medicine show
that in patients who have chronic hepatitis C, genotype 1 -- the most common
form of the disease and difficult to treat successfully

 May 26 04

Histopathological Effects of Pegylated and Standard Interferon in Responders and Non Responders Chronic Hepatitis C Genotype 4

May 2004


 

2003 Articles


Pegasys as Monotherapy or in Combination with Ribavirin Significantly Improves End of Treatment Response Rate in HCV Genotype 4 Chronic Active Hepatitis (CAH) Patients

Liver Steatosis (fatty liver) Is Associated with HCV Genotype 3 but Not with Fibrosis

Patients with High HCV Viral Load, Genotype 1 and Cirrhosis May Require More Than 48 Weeks Combination Therapy with Pegasys + Copegus

HCV Genotype 6 Is More Responsive to Therapy Than Genotype 1

Short (14 Weeks) Combination Treatment with PEG-Intron Plus Ribavirin Produces a High Sustained Response Rate in Patients with HCV Genotype 2/3

The Degree of Steatosis Is Related to That of Fibrosis and the Impact Is More Marked in Genotype 1 Than in Genotype 3 Patients with Chronic HCV

Impact of Steatosis on Baseline Characteristic and End of Treatment Response in Chronic HCV Genotype 4 Patients Treated with Rebetron or PEG-Intron Plus Ribavirin

Treatment with Peginterferon or Interferon Alfa and Ribavirin Leads to Reduction or Disappearance of Liver Steatosis, Especially in Genotype 3 Sustained Responders

Prolonged Interferon Therapy (72 Weeks) Could Be Worthwhile Treatment Strategy for Chronic HCV Patients with HCV Genotype 1b and a High Virus Load

Early Viral Kinetics in Chronic Hepatitis C Virus Genotype 4

HepCgen genotyping service helps fight Hepatitis C, a ‘silent epidemic’

Should PEG-Intron Be Given Twice Weekly to Improve HCV Clearance in Genotype 1 Patients?

HCV Patients with Genotype 4 Are Significantly More Likely to Develop Severe Fibrosis or Cirrhosis Post Liver Transplantation

Following Treatment with Interferon and Ribavirin, Fibrosis Regression Is Greater in HCV Genotype 1 Sustained Responders But Also May Decrease in Non Responders

Sustained Viral Response to Treatment Is Associated with a Reduction of Steatosis in Genotype 3 HCV Patients

Slow Viral Dynamics of Hepatitis C Virus Genotype 4

Shorter Interferon/Ribavirin Course Effective for Chronic Hepatitis C Types 2&3

Race, Insulin Resistance, Visceral Adiposity and Hepatic Steatosis in Genotype 1 HCV Patients  

   

2002 Thru 2001 Articles


 Hepatitis C Genotype not responsible for serious liver disease

Pegylated Interferon and Genotypes

Schering-Plough Reports Phase III PEG-INTRON(TM) Plus REBETOL(R)Results at American Association For The Study of Liver Diseases Meeting (Results on different Genotypes)

Info: HCV Genotypes and Cyroglobulinaemia

Hepatitis c virus genotypes Linked to Cirrhosis

What the genotypes are, and factors which may influence outcome

DOES GENOTYPE PLAY ROLE IN HCV PROGRESSION?

Hepatitis Therapy should be individually Tailored

Amount of Hepatic Hepatitis C Virus-RNA Not Correlated With Disease Severity

Genotype An Actor In Acute Hepatitis C Outcome

SLOW VIRAL DYNAMICS OF HEPATITIS C GENOTYPE 4

Genotypes and Quasispecies

Viral genotype, alcohol influence hepatitis C outcome

Genetic Complexity of Hepatitis C Virus

AcroMetrix Introduces Hepatitis C Genotyping Panel to the Clinical Laboratory Market (he genotype of HCV has been shown to be an independent predictor of sustained virologic response to antiviral drugs )

Viral Load not Dependent on Genotype

HCV Genotype May Influence Immune Response

By Brian Boyle, MD

High-dose IFN induction best for HCV genotype one

J Hepatology 2002; 37: 124–130
 

 

 

 

 

          
 
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 Reviewed Nov 15 2004